β-Apopicropodophyllin functions as a radiosensitizer targeting ER stress in non-small cell lung cancer
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چکیده
منابع مشابه
Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer.
Signaling pathways that activate mTOR (mammalian target of rapamycin) are altered in many human cancers and these alterations are associated with prognosis and treatment response. mTOR inhibition can restore sensitivity to DNA damaging agents such as cisplatin. The rapamycin derivative everolimus exhibits antitumor activity and is approved for pat...
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ژورنال
عنوان ژورنال: Biomedicine & Pharmacotherapy
سال: 2019
ISSN: 0753-3322
DOI: 10.1016/j.biopha.2019.108769